
ELK Biotechnology Bak rabbit pAb
인간 Bak 단백질을 인식하는 rabbit polyclonal antibody로, WB, IHC, IF, ELISA에 적합합니다. 미토콘드리아 외막 단백질 검출에 사용되며, 세포 자멸사 관련 연구에 유용합니다. 고순도 IgG, 1 mg/ml 농도, -20°C 보관.
- 판매단위
- pk
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제품명
Bak rabbit pAb
공급업체
ELK Biotechnology
대체 명칭
BAK1; BAK; BCL2L7; CDN1; Bcl-2 homologous antagonist/killer; Apoptosis regulator BAK; Bcl-2-like protein 7; Bcl2-L-7
응용 분야
- WB (Western Blot)
- IHC (Immunohistochemistry)
- IF (Immunofluorescence)
- ELISA
권장 희석 배율
| 실험 종류 | 희석 배율 |
|---|---|
| Western Blot | 1/500 - 1/2000 |
| IHC-p | 1/100 - 1/300 |
| ELISA | 1/20000 |
| IF | 1/100 - 1/300 |
| 기타 | Not yet tested in other applications |
면역원 (Immunogen)
The antiserum was produced against synthesized peptide derived from human Bak.
AA range: 1–50
스펙 정보
| 항목 | 내용 |
|---|---|
| Host | Rabbit |
| 저장 조건 | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| 농도 | 1 mg/ml |
| 관찰된 밴드 | 25 kD |
| Gene ID (Human) | 578 |
| Human Swiss-Prot No | Q16611 |
| 세포 내 위치 | Mitochondrion outer membrane; Single-pass membrane protein |
| Species Reactivity | Human; Mouse |
배경 정보
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators involved in a wide variety of cellular activities. This protein localizes to mitochondria and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, leading to a loss in membrane potential and the release of cytochrome c. It also interacts with the tumor suppressor P53 after exposure to cell stress.
[provided by RefSeq, Jul 2008]
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