ELK Biotechnology ATP5H rabbit pAb
ATP5H 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 사용 가능. 인간, 생쥐, 랫트 반응성. 미토콘드리아 내막 단백질 검출에 적합. 고순도 IgG, 1 mg/ml 농도, -20°C에서 1년 보관 가능.
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제품명
ATP5H rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | ATP5H; My032; ATP synthase subunit d; mitochondrial; ATPase subunit d |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ATP5H (AA range: 111–160) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 26 kD |
| Gene ID (Human) | 10476 |
| Human Swiss-Prot No. | O75947 |
| Cellular Localization | Mitochondrion, inner membrane |
| Species Reactivity | Human; Mouse; Rat |
Background
Mitochondrial ATP synthase catalyzes ATP synthesis by utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It consists of two linked multi-subunit complexes: the soluble catalytic core (F1) and the membrane-spanning component (Fo), which forms the proton channel. The F1 complex contains five different subunits (α, β, γ, δ, ε) assembled in a ratio of 3α:3β:1γ:1δ:1ε. The Fo complex includes nine subunits (a, b, c, d, e, f, g, F6, and 8). This gene encodes the d subunit of the Fo complex. Alternatively spliced transcript variants encoding different isoforms have been identified, and three pseudogenes are located on chromosomes 9, 12, and 15 (RefSeq, Jun 2010).
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