ELK Biotechnology AQP4 rabbit pAb
AQP4 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 적합합니다. 인간 AQP4 유래 펩타이드로 면역화되었으며, 35kDa 밴드를 검출합니다. 뇌 수분 항상성 연구 및 신경세포막 단백질 분석에 유용합니다.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology AQP4 rabbit pAb
ELK Biotechnology AQP4 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | AQP4 rabbit pAb |
| Alternative Names | AQP4; Aquaporin-4; AQP-4; Mercurial-insensitive water channel; MIWC; WCH4 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 ELISA: 1/5000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human AQP4 (AA range: 204-253) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 35 kD |
| Gene ID (Human) | 361 |
| Human Swiss-Prot No | P55087 |
| Species Reactivity | Human; Mouse; Rat |
세포 내 위치 (Cellular Localization)
Cell membrane; Multi-pass membrane protein.
Basolateral cell membrane; Multi-pass membrane protein.
Endosome membrane.
Cell membrane, sarcolemma; Multi-pass membrane protein.
Cell projection.
Activation of the vasopressin receptor AVPR1A triggers AQP4 phosphorylation at Ser-180 and promotes its internalization from the cell membrane.
Detected on brain astrocyte processes and astrocyte endfeet close to capillaries.
Background
This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells.
This protein is the predominant aquaporin found in the brain and has an important role in brain water homeostasis.
Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.
[provided by RefSeq, Dec 2015]
ELK Biotechnology 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.