ELK Biotechnology Aldose Reductase rabbit pAb
Aldose Reductase rabbit polyclonal antibody for WB, IHC, IF, and ELISA applications. Recognizes human AKR1B1 with cytoplasmic localization. High specificity and stability with long-term storage at -20°C.
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Aldose Reductase rabbit pAb
Supplier: ELK Biotechnology
제품 정보
| 항목 | 내용 |
|---|---|
| Product Name | Aldose Reductase rabbit pAb |
| Alternative Names | AKR1B1; ALDR1; Aldose reductase; AR; Aldehyde reductase; Aldo-keto reductase family 1 member B1 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 Immunofluorescence: 1/200 - 1/1000 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human AKR1B1 (AA range: 241–290) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 36 kD |
| GeneID (Human) | 231 |
| Human Swiss-Prot No | P15121 |
| Cellular Localization | Cytoplasm |
| Species Reactivity | Human; Rat |
Background
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. (provided by RefSeq, Feb 2009)
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