ELK Biotechnology Ah Receptor rabbit pAb
Ah Receptor rabbit polyclonal antibody for WB, IHC, IF, ELISA applications. Recognizes human, mouse, and rat AhR protein. Targets ligand-activated transcription factor regulating xenobiotic metabolism. Stable at -20°C for 1 year with 1 mg/ml concentrat...
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제품명
Ah Receptor rabbit pAb
공급업체
ELK Biotechnology
대체 명칭
AHR; BHLHE76; Aryl hydrocarbon receptor; Ah receptor; AhR; Class E basic helix-loop-helix protein 76; bHLHe76; AHRR; BHLHE77; KIAA1234; Aryl hydrocarbon receptor repressor; AhR repressor; AhRR; Class E basic helix-loop-helix protein 77; bHL
적용 분야
WB, IHC, IF, ELISA
권장 희석 배율
- Western Blot: 1/500 - 1/2000
- Immunohistochemistry: 1/100 - 1/300
- Immunofluorescence: 1/200 - 1/1000
- ELISA: 1/20000
※ 기타 응용은 아직 테스트되지 않음
면역원
Synthesized peptide derived from human AhR (AA range: 2–51)
보관 정보
- 종: Rabbit
- 온도: -20°C
- 유효기간: 1년
항체 특성
| 항목 | 내용 |
|---|---|
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 96 kD |
| GeneID (Human) | 196 / 57491 |
| Human Swiss-Prot No | P35869 / A9YTQ3 |
| Cellular Localization | Cytoplasm, Nucleus. Initially cytoplasmic; upon ligand binding and interaction with HSP90, translocates to the nucleus. |
| Species Reactivity | Human, Mouse, Rat |
배경 정보
The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor regulates xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, it moves to the nucleus and stimulates transcription of target genes.
(RefSeq, Sep 2015)
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