ELK Biotechnology 14-3-3 ε rabbit pAb
14-3-3 ε 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 적합합니다. 인산화 세린 결합 단백질 신호전달 연구에 활용되며, 인간·마우스·랫트 반응성이 있습니다. -20°C에서 1년 보관 가능합니다.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology 14-3-3 ε rabbit pAb
제품명
14-3-3 ε rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | YWHAE; 14-3-3 protein epsilon; 14-3-3E |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 Immunofluorescence: 1/200 - 1/1000 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human 14-3-3 epsilon (AA range: 206-255) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 29 kD |
| Gene ID (Human) | 7531 |
| Human Swiss-Prot No. | P62258 |
| Cellular Localization | Nucleus, Cytoplasm, Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
| Species Reactivity | Human, Mouse, Rat |
배경 (Background)
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008]
ELK Biotechnology 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.