ELK Biotechnology Tensin-1 (phospho Tyr1326) rabbit pAb
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| Product name: | Tensin-1 (phospho Tyr1326) rabbit pAb |
| Alternative Names: | TNS1; TNS; Tensin-1 |
| Applications: | WB;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | Synthesized phospho-peptide around the phosphorylation site of human Tensin-1 (phospho Tyr1326) |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 185kD |
| GeneID（Human）: | 7145 |
| Human Swiss-Prot No: | Q9HBL0 |
| Cellular localization: | Cell surface . Cell junction, focal adhesion . Cytoplasm, cytoskeleton . Localized at cell periphery preferentially to fibrillar adhesions than focal adhesions. Translocates from the cell edge to cell center in an ITGB1BP1-dependent manner. |
| Background: | The protein encoded by this gene localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. This protein is a substrate of calpain II. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015], |
| Species Reactivity: | Human;Mouse |
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