ELK Biotechnology Caldesmon (phospho Ser789) rabbit pAb
Caldesmon (phospho Ser789) rabbit pAb는 인산화된 Caldesmon 단백질을 인식하는 고품질 폴리클로날 항체입니다. WB, IHC, IF, ELISA 등 다양한 응용에 적합하며, 사람·생쥐·쥐 시료에서 반응합니다. 세포골격 및 평활근 수축 조절 연구에 유용합니다.
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Caldesmon (phospho Ser789) rabbit pAb
제품 개요
Caldesmon (phospho Ser789) rabbit pAb는 인간 Caldesmon 단백질의 Ser789 인산화 부위를 인식하도록 제작된 폴리클로날 항체입니다. 세포골격 및 평활근 수축 조절 관련 연구에 활용할 수 있습니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Caldesmon (phospho Ser789) rabbit pAb |
| Alternative Names | CALD1; CAD; CDM; Caldesmon; CDM |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC: 1/100–1/300 IF: 1/200–1/1000 ELISA: 1/5000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human Caldesmon around Ser789 (AA range: 744–793) |
| Species Reactivity | Human; Mouse; Rat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 80 kD |
| Gene ID (Human) | 800 |
| Human Swiss-Prot No | Q05682 |
| Cellular Localization | Cytoplasm, cytoskeleton, myofibril, stress fiber. On thin filaments in smooth muscle and on stress fibers in fibroblasts (nonmuscle). |
| Storage | -20°C / 1 year |
| Host | Rabbit |
Background
This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. (provided by RefSeq, Jul 2008)
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