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ELK Biotechnology IGF-IR (phospho Tyr1161) rabbit pAb
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ELK Biotechnology IGF-IR (phospho Tyr1161) rabbit pAb

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IGF-IR (phospho Tyr1161) rabbit pAb는 인슐린 유사 성장인자 수용체의 인산화 상태를 검출하는 항체입니다. WB, IHC, IF, ELISA에 사용 가능하며 인간, 마우스, 랫트에 반응합니다. 세포막 단백질 연구 및 암 관련 신호전달 분석에 적합합니다.

판매단위
pk
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ELK Biotechnology ES1515-100UL IGF-IR (phospho Tyr1161) rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES1515-50UL IGF-IR (phospho Tyr1161) rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology IGF-IR (phospho Tyr1161) rabbit pAb

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IGF-IR (phospho Tyr1161) rabbit pAb

제품 정보

항목 내용
Alternative Names IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221; INSR; Insulin receptor; IR; CD antigen CD220
Applications WB; IHC; IF; ELISA
Recommended Dilutions Western Blot: 1/500 - 1/2000
Immunohistochemistry: 1/100 - 1/300
Immunofluorescence: 1/200 - 1/1000
ELISA: 1/40000
Not yet tested in other applications
Immunogen Synthesized phospho-peptide around the phosphorylation site of human IGF-IR (phospho Tyr1161)
Host Rabbit
Storage -20°C / 1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band pro: 155 kD, receptor beta: 95 kD
Gene ID (Human) 3480
Human Swiss-Prot No. P08069 / P06213
Cellular Localization Cell membrane; Single-pass type I membrane protein
Species Reactivity Human; Mouse; Rat

Background

This receptor binds insulin-like growth factor with a high affinity and has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
[Provided by RefSeq, May 2014]

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