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ELK Biotechnology FAK (phospho Tyr397) rabbit pAb
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FAK (phospho Tyr397) rabbit pAb는 인간, 마우스, 랫트 시료에서 사용 가능한 인산화 FAK 검출용 항체입니다. WB, IHC, IF, ELISA에 적합하며 Tyr397 인산화 부위 특이적 반응을 보입니다. 고순도 폴리클로날 IgG로 -20°C에서 1년 보관 가능합니다.
- 판매단위
- pk
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ELK Biotechnology ES1492-100UL FAK (phospho Tyr397) rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES1492-50UL FAK (phospho Tyr397) rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology FAK (phospho Tyr397) rabbit pAb
제품명
FAK (phospho Tyr397) rabbit pAb
공급업체
ELK Biotechnology
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | PTK2; FAK; FAK1; Focal adhesion kinase 1; FADK 1; Focal adhesion kinase-related nonkinase; FRNK; Protein phosphatase 1 regulatory subunit 71; PPP1R71; Protein-tyrosine kinase 2; p125FAK; pp125FAK |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 ELISA: 1/5000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human FAK around the phosphorylation site of Tyr397 (AA range: 363-412) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 119 kD |
| GeneID (Human) | 5747 |
| Human Swiss-Prot No. | Q05397 |
| Cellular Localization | Cell junction, focal adhesion; Cell membrane (peripheral membrane protein, cytoplasmic side); Cytoplasm (cell cortex, cytoskeleton, microtubule organizing center, centrosome, cilium basal body); Nucleus; Constituent of focal adhesions; Detected at microtubules |
| Species Reactivity | Human; Mouse; Rat |
Background
Protein tyrosine kinase 2 (PTK2) is a cytoplasmic protein tyrosine kinase concentrated in focal adhesions formed between cells and extracellular matrix components. It belongs to the FAK subfamily of protein tyrosine kinases and plays an essential role in cell growth and intracellular signaling pathways triggered by neural peptides or cell-matrix interactions. Multiple transcript variants encoding different isoforms have been identified for this gene, with four full-length forms determined (RefSeq, Oct 2015).
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