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ELK Biotechnology c-Fos (phospho Ser362) rabbit pAb
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c-Fos (phospho Ser362) rabbit polyclonal antibody로, 인산화된 Ser362 부위를 특이적으로 인식합니다. Western blot, IHC, IF, ELISA 등 다양한 응용에 적합하며, 인간, 생쥐, 랫트 시료에 반응합니다. 세포 성장 및 분화 연구에 활용 가능합니다.
- 판매단위
- pk
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ELK Biotechnology ES1483-100UL c-Fos (phospho Ser362) rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES1483-50UL c-Fos (phospho Ser362) rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology c-Fos (phospho Ser362) rabbit pAb
제품명
c-Fos (phospho Ser362) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | FOS; G0S7; Proto-oncogene c-Fos; Cellular oncogene fos; G0/G1 switch regulatory protein 7 |
| Applications | WB; CoIP; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500–1/2000 Immunohistochemistry: 1/100–1/300 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Fos around the phosphorylation site of Ser362 (AA range: 331–380). |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 62 kD |
| Gene ID (Human) | 2353 |
| Human Swiss-Prot No. | P01100 |
| Species Reactivity | Human; Mouse; Rat |
| Cellular Localization | Nucleus, Endoplasmic reticulum, Cytoplasm (cytosol). In quiescent cells, present in very small amounts in the cytosol. Following induction of cell growth, first localizes to the endoplasmic reticulum and later to the nucleus. Localization at the endoplasmic reticulum requires dephosphorylation at Tyr-10 and Tyr-30. |
Background
The Fos gene family consists of four members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with JUN family proteins to form the transcription factor complex AP-1. FOS proteins regulate cell proliferation, differentiation, and transformation, and their expression can also be associated with apoptotic cell death.
[Provided by RefSeq, Jul 2008]
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