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ELK Biotechnology GSK3β (phospho Ser9) rabbit pAb
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GSK3β (phospho Ser9) 인산화 부위를 인식하는 토끼 다클론 항체로, WB, IHC, IF, ELISA에 적합합니다. 세포질 및 세포막에서 발현된 인산화형 GSK3β 검출에 유용하며, 인간, 마우스, 랫트 시료에 반응합니다.
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- pk
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ELK Biotechnology ES1420-100UL GSK3β (phospho Ser9) rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES1420-50UL GSK3β (phospho Ser9) rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology GSK3β (phospho Ser9) rabbit pAb
제품명
GSK3β (phospho Ser9) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | GSK3B; Glycogen synthase kinase-3 beta; GSK-3 beta; Serine/threonine-protein kinase GSK3B |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | Synthesized phospho-peptide around the phosphorylation site of human GSK3β (phospho Ser9) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 47 kD |
| Gene ID (Human) | 2932 |
| Human Swiss-Prot No. | P49841 |
| Cellular Localization | Cytoplasm, Nucleus, Cell membrane. The phosphorylated form shows localization to cytoplasm and cell membrane (PubMed:20937854). The MEMO1-RHOA-DIAPH1 signaling pathway controls localization of the phosphorylated form to the cell membrane (PubMed:20937854). |
| Species Reactivity | Human; Mouse; Rat |
Background
The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson’s disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer’s disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
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