Thermo Fisher Scientific MAD3 Polyclonal Antibody
Thermo Fisher Scientific의 MAD3 Polyclonal Antibody는 인간 및 생쥐 시료에서 MXD3 단백질을 검출하는 토끼 유래 다클론 항체입니다. Western blot과 IHC(P)에서 사용 가능하며, 고순도 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
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- PA5102965
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MXD3 (Accession Q9BW11), corresponding to amino acid residues Q131–G181. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852339 |
Product Specific Information
Antibody detects endogenous levels of total MXD3.
Target Information
This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX, which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX–MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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