Thermo Fisher Scientific CHRM1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000-1:2,500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human CHRM1. Recombinant protein control fragment (Product #RP-90876). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CHRM1,uniProtId:P11229-1,ncbiNodeId:9606,antigenRange:228-360,antigenLength:460,antigenImageFileName:PA5-53124_CHRM1_P11229-1_Rabbit.svg,antigenImageFileNamePDP:PA5-53124_CHRM1_P11229-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.19 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2639793

Product Specific Information

Immunogen sequence: SETPGKGGGS SSSSERSQPG AEGSPETPPG RCCRCCRAPR LLQAYSWKEE EEEDEGSMES LTSSEGEEPG SEVVIKMPMV DPEAQAPTKQ PPRSSPNTVK RPTKKGRDRA GKGQKPRGKE QLAKRKTFSL VKE

Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 97%.

Target Information

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.