Thermo Fisher Scientific Phospho-XRCC1 (Ser485, Thr488) Polyclonal Antibody
XRCC1 단백질의 Ser485 및 Thr488 인산화 부위를 인식하는 Rabbit Polyclonal Antibody. Western blot 및 IHC에 적합하며, 인간 및 마우스 시료 반응. 항원 친화 크로마토그래피로 정제된 액상 형태, 4°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
Immunohistochemistry (IHC)
- Tested Dilution: 1:2,000–1:10,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:2,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region surrounding residues Ser 485 and Thr 488 of Human X-ray Repair Complementing protein 1 (XRCC1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
- Based on 100% sequence identity, this antibody is predicted to react with Rat.
Target Information
XRCC1 (X-ray cross complementing factor-1) is involved in DNA base excision repair.
It is a 70 kDa protein that interacts with DNA repair enzymes such as poly (ADP-ribose) polymerase (PARP), DNA Ligase III, and DNA polymerase beta.
XRCC1 contains a BRCT domain (BRCA1 carboxyl terminus), which mediates protein-protein interactions with DNA ligase III-alpha.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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