Thermo Fisher Scientific SESN3 Polyclonal Antibody
인간 SESN3 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot 및 ELISA에 적합합니다. Affinity Chromatography로 정제되었으며, PBS/glycerol buffer에 보관됩니다. 세포 내 leucine 감지 및 TORC1 신호 조절 연구에 유용합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–310 of human SESN3 (NP_6532662) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.4 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806447 |
Product Specific Information
Immunogen sequence:
MNRGGGSPSA AANYLLCTNC RKVLRKDKRI RVSQPLTRGP SAFIPEKEVV QANTVDERTN FLVEEYSTSG RLDNITQVMS LHTQYLESFL RSQFYMLRMD GPLPLPYRHY IAIMAAARHQ CSYLINMHVD EFLKTGGIAE WLNGLEYVPQ RLKNLNEINK LLAHRPWLIT KEHIQKLVKT GENNWSLPEL VHAVVLLAHY HALASFVFGS GINPERDPEI SNGFRLISVN NFCVCDLAND NNIENASLSG SNFGIVDSLS ELEALMERMK RLQEEREDEE ASQEEMSTRF EKEKKESLFV VSGDTFHSFP
Positive Samples: HeLa, A-549
Target Information
SESN3 may function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway (PubMed:25263562). It may also regulate the insulin-receptor signaling pathway through activation of TORC2. This metabolic regulator may play a role in protection against oxidative and genotoxic stresses.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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