Thermo Fisher Scientific LMAN1 Monoclonal Antibody (2B4)
Thermo Fisher Scientific의 LMAN1 Monoclonal Antibody (2B4)는 mouse LMAN1 단백질을 인식하는 rat IgG1 형의 단클론 항체로, Western blot 및 inhibition assay에 적합합니다. Calcium 의존적 결합 특성을 가지며 연구용으로만 사용됩니다.
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Applications
- Western Blot (WB): 1:50
- Inhibition Assays (IA): 1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rat / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2B4 |
| Immunogen | Purified mouse MBL-A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 100 µg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
| RRID | AB_3091128 |
Product Specific Information
The monoclonal antibody 2B4 is a calcium-dependent antibody.
Target Information
The protein encoded by the LMAN1 gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi apparatus, recycling between these compartments.
It functions as a mannose-specific lectin and belongs to a novel family of plant lectin homologs in the secretory pathway of animal cells.
Mutations in this gene are associated with a coagulation defect, identified as the cause of combined factor V-factor VIII deficiency, a rare autosomal recessive disorder in which both coagulation factors V and VIII are diminished.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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