Thermo Fisher Scientific CADM1 Polyclonal Antibody
Thermo Fisher Scientific의 CADM1 Polyclonal Antibody는 마우스 시료에 반응하며 Western Blot에 최적화된 고순도 항체입니다. 비결합형 액상 포맷으로 제공되며, 암모늄 황산염 침전으로 정제되었습니다. CADM1 단백질의 다양한 생물학적 기능 연구에 적합합니다.
- 카탈로그번호
- PA5142836
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1–3 µg/mL
- Tested in Peptide ELISA: Antibody detection limit dilution 1:8,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-QLYTDPPQESYTT |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933479 |
Product Specific Information
This antibody is expected to recognize both reported isoforms (NP_055148.3; NP_001091987.1).
Target Information
CADM1 mediates homophilic cell-cell adhesion in a Ca²⁺-independent manner and heterophilic adhesion with CADM3 and PVRL3. It acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM enhances NK cell cytotoxicity and IFN-γ secretion by CD8⁺ cells. CADM1 contributes to the less invasive phenotype of lepidic growth tumor cells and plays roles in mast cell communication, neuronal development, and spermatogenesis.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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