Thermo Fisher Scientific ASB2 Monoclonal Antibody (OTI2A2)
ASB2 단백질을 인식하는 마우스 단클론 항체로 인간 시료에 반응합니다. IHC(P) 실험에 사용 가능하며, 고순도 친화 크로마토그래피로 정제되었습니다. PBS 기반 완충액에 보관하며 -20°C에서 안정적으로 저장됩니다. 연구용으로만 사용됩니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–300 of ASB2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723915 |
Target Information
The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequences and a SOCS box domain. The SOCS box couples suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. This gene is induced by all-trans retinoic acid. In myeloid leukemia cells, the expression of this protein has been shown to induce growth inhibition and chromatin condensation. Multiple alternatively spliced transcript variants have been described for this gene but their full-length sequences are not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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