Thermo Fisher Scientific CD44 Monoclonal Antibody (MEM-85), FITC

Applications

• Flow Cytometry (Flow): Assay-dependent
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• Miscellaneous PubMed (Misc): –
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Product Specifications

Product Specific Information

FITC conjugates provide high absorptivity, excellent fluorescence quantum yield, and good water solubility, making them suitable for flow cytometry and fluorescence-based assays.

Target Information

CD44 is a 100 kDa type I transmembrane glycoprotein expressed on human leukocytes, brain white matter, and various epithelial cells. It acts as a receptor for hyaluronic acid (HA) and plays roles in cell-cell interaction, adhesion, and migration.
CD44 is involved in lymphocyte activation, recirculation, and homing. Expression levels can increase in certain carcinomas, potentially linked to metastatic potential.
Multiple isoforms exist due to complex alternative splicing, contributing to structural and functional diversity.
Diseases associated with CD44 dysfunction include superficial keratitis and lichen sclerosus, and the protein may be related to tumor metastasis formation.

Additional Formats

• PE conjugate
• Request custom conjugation

Analyte Specific Reagent

For research use only. Not for diagnostic or therapeutic applications.

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