Thermo Fisher Scientific Histone Deacetylase 1 (HDAC3) Monoclonal Antibody (PCRP-HDAC3-3C9)
HDAC3 단백질을 표적으로 하는 Thermo Fisher Scientific의 Mouse Monoclonal 항체입니다. Western blot, ICC/IF, Flow Cytometry, ELISA, IP 등 다양한 응용에 사용 가능하며, 인간 HDAC3 단백질에 반응합니다. 고순도 Protein A/G 정제, 4°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
| ELISA | Assay-dependent |
| Immunoprecipitation (IP) | 1–2 µg/500 µg lysate |
| Peptide Array | Assay-dependent |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PCRP-HDAC3-3C9 |
| Immunogen | Recombinant full-length human HDAC3 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA.
HDAC3 belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in transcription regulation through binding with the zinc-finger transcription factor YY1.
This protein can also down-regulate p53 function, modulating cell growth and apoptosis. The HDAC3 gene is regarded as a potential tumor suppressor gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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