Thermo Fisher Scientific TSC22D1 Monoclonal Antibody (PCRP-TSC22D1-1A2)
TSC22D1 단백질을 인식하는 마우스 단일클론 항체로, Western blot, ICC/IF, Flow cytometry 등에 사용 가능. 인간 시료 반응성, Protein A/G 정제, 액상 형태로 제공. 세포 성장 및 분화 관련 연구에 적합한 연구용 항체.
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- 8848-MSM1-P1
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PCRP-TSC22D1-1A2 |
| Immunogen | Recombinant full-length human TSC22D1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
TSC22 domain family protein (TSC22) is a transcription factor belonging to the large family of early response genes. It acts as a transcriptional repressor on the C-type natriuretic peptide (CNP) promoter and is part of the TSC-22/Dip/Bun family. TSC22 is an intracellular protein localized in the cytoplasm or nucleus and plays a role in regulating cell growth, differentiation, and apoptosis. It modulates the transcriptional activity of Smad3 and Smad4 and is ubiquitously expressed in both fetal and adult tissues, including aortic endothelial cells. Expression is induced by cytokines such as TGFB. TSC22 proteins may serve as potential therapeutic targets for leukemia and prostate cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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