Thermo Fisher Scientific SLC11A1 Polyclonal Antibody, MaxPab

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG

Class

Polyclonal

Type

Antibody

Immunogen

SLC11A1 (AAH41787.1, 1 a.a. approximately 178 a.a) full-length human protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SLC11A1,uniProtId:P49279-1,ncbiNodeId:9606,antigenRange:1-550,antigenLength:550,antigenImageFileName:H00006556-B01P_SLC11A1_P49279-1_House_mouse.svg,antigenImageFileNamePDP:H00006556-B01P_SLC11A1_P49279-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MTGDKGPQRL SGSSYGSISS PTSPTSPGPQ QAPPRETYLR NIESDLQAGA VAGFKLLWVL LWATVLGLLC QRLAARLGVV TGKDLGEVCH LYYPKVPRTV LWLTIELAIV GSDMQEVIGT AIAFNLLSAG RYHPSVPQLF RPGREQLLLL PPLTSPSQSL FYPAVPSEAG LLPCFPEM

Target Information

NRAMP1, also known as SLC11A1, is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and encodes a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in this gene have been associated with susceptibility to infectious diseases such as leprosy and tuberculosis, and inflammatory diseases such as Crohn disease and rheumatoid arthritis. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.