Thermo Fisher Scientific SLC22A2 Monoclonal Antibody (1E3)
SLC22A2 단백질을 인식하는 마우스 단클론 항체로, Western blot과 ELISA에 적합합니다. Human 시료에 반응하며, PBS(pH 7.4) 용액에 보존됩니다. 친화 크로마토그래피로 정제되었으며, 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.3 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1E3 |
| Immunogen | SLC22A2 (AAH39899, 261 a.a. ~ 370 a.a) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
HWRWLQFTVA LPNFFFLLYY WCIPESPRWL ISQNKNAEAM RIIKHIAKKN GKSLPASLQR LRLEEETGKK LNPSFLDLVR TPQIRKHTMI LMYNWFTSSV LYQGLIKHMG
Target Information
Organic cation transporters (OCT) are expressed in the plasma membrane of epithelial cells from a wide range of tissues, where they function in the elimination of endogenous amines, cationic drugs, and other xenobiotics. The structure of OCTs consists of a 12-transmembrane-domain structure and a large extracellular hydrophilic loop.
In humans:
- OCT1 is primarily expressed in the liver
- OCT2 is expressed in the kidney
- OCT3 is expressed in the placenta, skeletal muscle, prostate, aorta, and liver
OCT2 (SLC22A2) is a multi-specific transporter protein localizing to the basolateral and luminal membranes of the kidney distal and proximal tubules. OCT2 mediates the pH-sensitive tubular uptake of organic compounds from circulation. An additional splice variant exists for OCT2, namely OCT2-A.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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