Thermo Fisher Scientific U2AF1L4 Monoclonal Antibody (OTI8F10), TrueMAB
U2AF1L4 단백질을 인식하는 Mouse 모노클로날 항체로, Western blot에 최적화되어 있습니다. 고순도 Affinity chromatography로 정제되었으며, 액상 형태로 제공됩니다. RNA 스플라이싱 관련 연구용으로 적합하며, -20°C에서 안정적으로 보관 가능합니다.
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Applications
- Western Blot (WB): Tested Dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8F10 |
| Immunogen | Full length human recombinant protein of human U2AF1L4 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
RNA-binding protein that functions as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein and protein-RNA interactions required for accurate 3'-splice site selection. Enhances the binding of U2AF2 to weak pyrimidine tracts and regulates alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T-cell activation; an event reversed by GFI1. Binds to RNA at the AG dinucleotide at the 3'-splice site, showing preference for AGC or AGA. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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