
Thermo Fisher Scientific PMS1 Monoclonal Antibody (OTI5E10), TrueMAB
인간 PMS1 단백질(aa 323-423)에 특이적인 mouse IgG1 단클론 항체. Western blot에 1:500~1:2,000 희석으로 사용 가능. Affinity chromatography로 정제된 액상형 항체로, PBS/BSA/glycerol buffer에 보관. DNA mismatch repair 연구용.
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Applications
- Western Blot (WB): Tested dilution 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5E10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 323–423 of human PMS1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. The PMS1 protein is involved in the repair of DNA mismatches and forms heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer type 3 (HNPCC3), also known as Lynch syndrome.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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