Thermo Fisher Scientific PRL1 Polyclonal Antibody
PRL1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC 등 다양한 응용에 적합. Human, Mouse, Rat 반응성. 고순도 친화 크로마토그래피 정제, 안정적인 PBS/glycerol buffer 보관. 연구용 전용 제품.
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Thermo Fisher Scientific PRL1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:30–1:150 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100 |
| Immunocytochemistry (ICC/IF) | 1:40–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein of human PRL1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2688527 |
Product Specific Information
Predicted to react with Mouse and Rat samples.
Target Information
The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contain a PTP domain and a characteristic C-terminal prenylation motif. PTPs are cell signaling molecules that play regulatory roles in various cellular processes. This tyrosine phosphatase is a nuclear protein but may primarily associate with the plasma membrane. The surface membrane association depends on its C-terminal prenylation. Overexpression in mammalian cells confers a transformed phenotype, implicating its role in tumorigenesis. Studies in rat suggest this gene may be an immediate-early gene in mitogen-stimulated cells. PRL phosphatases increase cell proliferation by stimulating progression from G1 into S phase. PRL-1 function is regulated in a cell cycle-dependent manner and may regulate progression through mitosis by modulating spindle dynamics.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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