Thermo Fisher Scientific RNF144B Monoclonal Antibody (OTI9H10), TrueMAB
Thermo Fisher Scientific의 RNF144B 단클론 항체(OTI9H10)는 인간 RNF144B 단백질을 인식하는 Mouse IgG2b 형 항체로, WB, IHC, ICC/IF, Flow Cytometry에 사용 가능. 고순도 친화 크로마토그래피 정제 및 안정적 PBS/BSA/glycerol 저장 포뮬러 제공.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI9H10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–256 of human RNF144B produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.8 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
E3 ubiquitin-protein ligase that accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 and transfers it to substrates such as LCMT2, promoting their degradation. Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism. Overexpression decreases ubiquitin-dependent stability of BAX, leading to protection from cell death, though it is not inherently anti-apoptotic.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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