Thermo Fisher Scientific Polysialic acid Recombinant Mouse Monoclonal Antibody (735)
Polysialic acid를 인식하는 Recombinant Mouse Monoclonal Antibody로 다양한 종(Human, Mouse, Rat)에 반응. Western blot, IHC, Flow cytometry 등 다중 응용 가능. HEK293 발현 시스템 기반, Protein A 정제, 1 mg/mL 농도.
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Applications
- Western Blot (WB): Assay-dependent
- Immunohistochemistry (IHC): Assay-dependent
- Flow Cytometry (Flow): Assay-dependent
- Immunoprecipitation (IP): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Mouse / IgG2a, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 735 |
| Immunogen | Homopolymers of α2,8-linked sialic acid of Escherichia coli K1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
Product Specific Information
Recognises Polysialic acid (PSA), a carbohydrate polymer attached to the neural cell adhesion molecule (NCAM), sharing molecular epitopes with homopolymers of α2,8-linked sialic acid of Escherichia coli K1.
Target Information
Polysialic acid is a glycan polymer composed of repeating units of sialic acid, forming a linear chain of α2,8-linked residues that can extend up to 200 units. This negatively charged molecule is found in cell membranes of bacteria and animals, playing critical roles in cell adhesion, migration, and neural development. It is also under investigation for therapeutic applications in cancer and neurological disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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