Thermo Fisher Scientific Polysialic acid Recombinant Mouse Monoclonal Antibody (735)

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

-

Immunohistochemistry (IHC)

Assay-dependent

-

Flow Cytometry (Flow)

Assay-dependent

-

Immunoprecipitation (IP)

Assay-dependent

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Mouse / IgG2a, kappa

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

735

Immunogen

Homopolymers of alpha2,8-linked sialic acid of Escherichia coli K1.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS

Contains

0.02% ProClin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

Product Specific Information

Recognises Polysialic acid (PSA), a carbohydrate polymer attached to the neural cell adhesion molecule (NCAM), which shares molecular epitopes with homopolymers of alpha 2,8-linked sialic acid of Escherichia coli K1.

Target Information

Polysialic acid is a glycan polymer composed of repeating units of the monosaccharide sialic acid. It consists of a linear chain of alpha-2,8-linked sialic acid residues that can extend up to 200 units in length. This negatively charged molecule is commonly present in the cell membranes of various organisms, including bacteria and animals, and plays a crucial role in regulating cell adhesion, migration, and neural development. Polysialic acid is also being explored for its potential therapeutic applications in the treatment of certain cancers and neurological disorders.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.