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Thermo Fisher Scientific PINK1 Monoclonal Antibody (N4/15), APC
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PINK1 단백질을 검출하기 위한 APC 결합 단클론 항체로, WB, IHC, ICC/IF 등 다양한 응용에 적합. 인간, 마우스, 랫트 반응성 보유. 단백질 G 정제, 1 mg/mL 농도, 4°C 보관. 미토콘드리아 기능 연구 및 파킨슨병 관련 연구용.
- 판매단위
- pk
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마지막 업데이트 2025. 08. 04. 오전 07:06
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Thermo Fisher Scientific MA545655 PINK1 Monoclonal Antibody (N4/15), APC 100 ug pk판매 단위 pk ·
재고 확인 필요
663,800원VAT 포함 730,180원
Thermo Fisher Scientific · Thermo Fisher Scientific PINK1 Monoclonal Antibody (N4/15), APC
Applications
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:1,000 | |
| Immunohistochemistry (IHC) | Assay-dependent | |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N4/15 |
| Immunogen | Fusion protein amino acids 112–496 (cytoplasmic C-terminus) of human PINK1 |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 2.48 mM MES / 95.64 mM phosphate, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932109 |
Additional Formats
- FITC ([MA5-45656])
- PerCP ([MA5-45657])
- Custom conjugation available upon request
Product Specific Information
- 82% identical to rat and 81% identical to mouse; >30% identity with DMPK
- 1 µg/mL of MA5-45655 detects PINK1 in 20 µg of rat brain lysate by colorimetric immunoblot using Goat anti-mouse IgG:HRP as secondary antibody
- Detects approximately 50 kDa
- Formerly sold as clone S4-15
Target Information
PINK1 (PTEN-induced putative kinase 1) protects cells from mitochondrial dysfunction through autophosphorylation activity affecting mitochondrial genes. The kinase domain of PINK1 is crucial for its protective effects. Mitochondrial proteins regulate cellular energy and stress adaptation, particularly in brain cells with high energy demands. Dysfunction of mitochondrial structure or function in the brain can lead to neurodegenerative diseases such as Parkinson’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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