Thermo Fisher Scientific COTL1 Polyclonal Antibody
Human COTL1 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot 및 IHC(P) 검증됨. 항원 친화 크로마토그래피로 정제된 액상 제품이며, 4°C 또는 -20°C 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human COTL1. Recombinant protein control fragment (Product #RP-88736). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640083 |
Product Specific Information
Immunogen sequence:
IWVTFKYDGS TIVPGEQGAE YQHFIQQCTD DVRLFAFVRF TTGDAMSKRS KFALITWIGE NVSGLQRAKT GTDKTLVKEV VQNFAKEFVI SDRKEL
Highest antigen sequence identity to orthologs:
- Mouse: 95%
- Rat: 96%
Target Information
This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin and also interacts with 5-lipoxygenase, the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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