
Thermo Fisher Scientific KCC3 Polyclonal Antibody
Rabbit polyclonal antibody targeting human KCC3 (SLC12A6) for WB and IP applications. Recognizes residues 25–75 of the protein. Supplied as liquid, 1 mg/mL, stored at 4°C. Predicted cross-reactivity with mouse. For research use only.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 | — |
| Immunoprecipitation (IP) | Assay-dependent | — |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 25–75 of human Potassium Chloride Cotransporter 3 (SLC12A6, UniProt ID: Q9UHW9-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
SLC12A6 (KCC3) belongs to the K-Cl cotransporter (KCC) family. These integral membrane proteins reduce intracellular chloride concentrations below the electrochemical equilibrium potential. They are activated by cell swelling under hypotonic conditions. Alternative splicing produces multiple isoforms. Mutations in SLC12A6 are associated with agenesis of the corpus callosum with peripheral neuropathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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