Thermo Fisher Scientific FZD2 Monoclonal Antibody (2C8)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

ELISA (ELISA)

1 ng/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b, kappa

Class

Monoclonal

Type

Antibody

Clone

2C8

Immunogen

FZD2 (NP_001457, 192 a.a. approximately 245 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Frizzled-2,uniProtId:Q14332-1,ncbiNodeId:9606,antigenRange:192-245,antigenLength:565,antigenImageFileName:H00002535-M01_Frizzled-2_Q14332-1_House_mouse.svg,antigenImageFileNamePDP:H00002535-M01_Frizzled-2_Q14332-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: YATLEHPFHC PRVLKVPSYL SYKFLGERDC AAPCEPARPD GSMFFSQEET RFAR

Target Information

This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. This gene encodes a protein that is coupled to the beta-catenin canonical signaling pathway. Competition between the wingless-type MMTV integration site family, member 3A and wingless-type MMTV integration site family, member 5A gene products for binding of this protein is thought to regulate the beta-catenin-dependent and -independent pathways.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.