Thermo Fisher Scientific ILK Recombinant Rabbit Monoclonal Antibody (SC68-04)
ILK 단백질을 표적하는 재조합 토끼 단일클론 항체로, WB, IHC, ICC/IF, Flow Cytometry에 사용 가능. HEK293 세포에서 발현되며 Protein A로 정제된 액상 형태. 인간, 마우스, 랫트 반응성. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SC68-04 |
| Immunogen | Synthetic peptide within human Integrin-linked kinase (ILK) aa 410–452 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at −20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2898915 |
Target Information
Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions and requires interaction of integrin cytoplasmic domains with cellular proteins.
Integrin-linked kinase (ILK) interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with four ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction.
Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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