Thermo Fisher Scientific TIM-4 Monoclonal Antibody (Kat5-18)
TIM-4 단백질을 표적으로 하는 Armenian hamster 유래 단클론 항체로, 세포 탐식 억제 기능 연구에 적합합니다. ICC/IF, Flow Cytometry, Functional Assay 등 다양한 응용 가능. 액상 형태로 4°C 보관하며 연구용으로만 사용됩니다.
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Thermo Fisher Scientific TIM-4 Monoclonal Antibody (Kat5-18)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1:50 |
| Flow Cytometry (Flow) | 1:50 |
| Functional Assay | 1:50 |
| Inhibition Assay (IA) | 1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Armenian hamster / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | Kat5-18 |
| Immunogen | Mouse peritoneal cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 100 µg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
| RRID | AB_3091068 |
Additional Formats
Product Specific Information
The monoclonal antibody Kat5-18 blocks the engulfment of apoptotic cells by thymic macrophages.
Target Information
The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors involved in the regulation of T helper (Th)-1 and Th-2 cell-mediated immunity.
TIM-4, preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM-1, leading to T-cell expansion and cytokine production.
Unlike other TIM family members, TIM-4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain.
The TIM-4 gene maps to a locus associated with predisposition to asthma in both mice and humans and, with its connection to TIM-1-triggered Th2 responsiveness, may be considered a candidate disease/predisposition gene for asthma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: MA5-49108_TIM-4_TIMD4_Q6U7R4-1_Armenian_hamster.svg / MA5-49108_TIM-4_TIMD4_Q6U7R4-1_Armenian_hamster_PDP.jpeg)
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배송/결제/교환/반품 안내
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