Thermo Fisher Scientific BAIAP2L1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 198-388 of human BAIAP2L1 (NP_061330.2). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:BAIAP2L1,uniProtId:Q9UHR4-1,ncbiNodeId:9606,antigenRange:198-388,antigenLength:511,antigenImageFileName:PA5-121180_BAIAP2L1_Q9UHR4-1_Rabbit.svg,antigenImageFileNamePDP:PA5-121180_BAIAP2L1_Q9UHR4-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.96 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2914752

Product Specific Information

Positive test controls include: HepG2, HeLa, 293T, A-549, Mouse lung. The target is usually found in the following locations: Cytoplasm, cytoskeleton.

Immunogen sequence: DKHCGFANHI HYYHLQSAEL LNSKLPRWQE TCVDAIKVPE KIMNMIEEIK TPASTPVSGT PQASPMIERS NVVRKDYDTL SKCSPKMPPA PSGRAYTSPL IDMFNNPATA APNSQRVNNS TGTSEDPSLQ RSVSVATGLN MMKKQKVKTI FPHTAGSNKT LLSFAQGDVI TLLIPEEKDG WLYGEHDVSK A

Target Information

This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.