Thermo Fisher Scientific HPa2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:100

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 42-242 of human HPSE2 (NP_068600.4). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:HPa2,uniProtId:Q8WWQ2-1,ncbiNodeId:9606,antigenRange:42-242,antigenLength:592,antigenImageFileName:PA5-121181_HPa2_Q8WWQ2-1_Rabbit.svg,antigenImageFileNamePDP:PA5-121181_HPa2_Q8WWQ2-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.67 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2914753

Product Specific Information

Positive test controls include: BT-474, 22Rv1, HeLa, SKOV3, Mouse brain, Mouse small intestine, Mouse testis, Mouse uterus, Rat brain. The target is usually found in the following locations: Secreted, extracellular matrix, extracellular space.

Immunogen sequence: GDRRPLPVDR AAGLKEKTLI LLDVSTKNPV RTVNENFLSL QLDPSIIHDG WLDFLSSKRL VTLARGLSPA FLRFGGKRTD FLQFQNLRNP AKSRGGPGPD YYLKNYEDDI VRSDVALDKQ KGCKIAQHPD VMLELQREKA AQMHLVLLKE QFSNTYSNLI LTARSLDKLY NFADCSGLHL IFALNALRRN PNNSWNSSSA L

Target Information

This gene encodes a heparanase enzyme. The encoded protein is a endoglycosidase that degrades heparin sulfate proteoglycans located on the extracellular matrix and cell surface. This protein may be involved in biological processes involving remodeling of the extracellular matrix including angiogenesis and tumor progression. Alternate splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.