Thermo Fisher Scientific FOXB1/FOXB2 Polyclonal Antibody
FOXB1/FOXB2 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 사람 및 마우스 시료 반응성이 있으며, 액상 형태로 제공됩니다. 친화 크로마토그래피로 정제되었으며, -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human FOXB1 (Accession Q99853), corresponding to amino acid residues P293–H325 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2815885 |
Product Specific Information
Antibody detects endogenous levels of total FOXB1/2.
Target Information
The Forkhead-box (FOX) genes comprise a superfamily of at least 43 members that encode proteins involved in transcriptional regulation and may be associated with the pathogenesis of various cancers.
FOXB1 (forkhead box B1), also known as FKH5 or HFKH-5, and FOXB2 (forkhead box B2) are members of the FOX family and each contain one forkhead DNA-binding domain. Both FOXB1 and FOXB2 localize to the nucleus, functioning as transcription factors that can bind DNA via their forkhead domains.
In mice, defects in the gene encoding FOXB1 are associated with retarded development of the central nervous system (CNS), suggesting that FOXB1 may play a role in CNS organization and function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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