Thermo Fisher Scientific BMP-3 Polyclonal Antibody
BMP-3 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 Immunocytochemistry에 적합합니다. 인간 시료에 반응하며, Affinity chromatography로 정제된 액상 형태입니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human BMP3 (Accession P12645), corresponding to amino acid residues R286–K336 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850899 |
Product Specific Information
Antibody detects endogenous levels of total BMP3.
Target Information
BMPs belong to the TGF-Beta superfamily. They stimulate the production of bone matrix proteins and influence stromal cell and osteoclast proliferation, which are key steps in bone marrow development.
In addition to promoting ectopic bone and cartilage development, BMPs regulate the growth, differentiation, chemotaxis, proliferation, and apoptosis of various cell types including mesenchymal, epithelial, hematopoietic, and neuronal cells.
BMPs also play a role in dorsal/ventral patterning. BMP3, highly expressed in lung, ovary, and small intestine, participates in cartilage and bone formation. BMP3 and BMP2 genes map to conserved regions between human and mouse.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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