Thermo Fisher Scientific PIMT Polyclonal Antibody
PIMT 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human에 반응하며 IHC 및 IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: 1:100–1:500
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 150 and 200 of Human PRIP-Interacting Protein with Methyltransferase Domain (Nuclear Receptor Coactivator 6 Interacting Protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Gorilla and Chimpanzee
Target Information
Catalyzes the two serial methylation steps for conversion of the 7-monomethylguanosine (m(7)G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, colocalization with coilin, and formation of canonical Cajal bodies (CBs). Plays a role in transcriptional regulation. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: IHC-00467_PIMT_Q96RS0-1_Rabbit.svg, IHC-00467_PIMT_Q96RS0-1_Rabbit_PDP.jpeg)
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