
Thermo Fisher Scientific MSR1 Monoclonal Antibody (OTI7H5), TrueMAB
MSR1 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI7H5). Western blot에서 1:2,000 희석으로 검증됨. Human 시료에 반응하며, PBS/BSA/glycerol buffer에 보관. CD204 관련 연구용으로 적합.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7H5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 197–451 of human MSR1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The CD204 (MSR1) gene encodes class A macrophage scavenger receptors, which include three isoforms (types 1, 2, and 3) generated by alternative splicing. These macrophage-specific trimeric membrane glycoproteins are involved in various physiological and pathological processes such as atherosclerosis, Alzheimer’s disease, and host defense.
- Type 1 and 2 isoforms: Functional receptors mediating endocytosis of modified LDLs.
- Type 3 isoform: Lacks endocytosis capability due to altered intracellular processing and retention in the endoplasmic reticulum. It may inhibit the function of types 1 and 2, suggesting a regulatory role in scavenger receptor activity.
Diseases associated with MSR1 include Barrett Esophagus and Prostate Cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
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