Thermo Fisher Scientific MSR1 Monoclonal Antibody (OTI8B11), TrueMAB
인간 MSR1 단백질(aa 197-451)을 타겟으로 하는 Mouse IgG1 단클론 항체. Western blot에 1:2000 희석으로 검증됨. 액상 형태, 1 mg/mL 농도, PBS/BSA/glycerol 버퍼에 보존. CD204 관련 대식세포 수용체 연구용으로 적합.
- 카탈로그번호
- TA802828
- 판매단위
- pk
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Applications
Tested Application
- Western Blot (WB): 1:2,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8B11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 197–451 of human MSR1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD204 gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and are implicated in various macrophage-associated physiological and pathological processes such as atherosclerosis, Alzheimer’s disease, and host defense.
- Isoforms type 1 and type 2: functional receptors mediating endocytosis of modified LDLs
- Isoform type 3: does not internalize modified LDL, trapped within the endoplasmic reticulum
- Type 3 isoform can inhibit types 1 and 2 when co-expressed (dominant negative effect)
Diseases associated with MSR1 include Barrett Esophagus and Prostate Cancer.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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