Thermo Fisher Scientific Syndecan 4 Polyclonal Antibody
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Syndecan-4 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, WB, IHC, ELISA 등 다양한 실험에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS buffer 내 0.1% sodium azide 함유. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | 4 publications |
| Immunohistochemistry (IHC) | - | 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:100 | - |
| Immunocytochemistry (ICC/IF) | - | 2 publications |
| ELISA | Assay-dependent | - |
| In vitro Assay (IV) | - | 1 publication |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mammal, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide derived from the middle region of the human Syndecan-4 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.1% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2533250 |
Target Information
Syndecans are type I integral membrane proteoglycans involved in cell-extracellular matrix adhesion and growth factor binding.
- Syndecan 1: Matrix receptor binding to Collagens, Fibronectin, and Thrombospondin.
- Syndecan 1 & 3: Interact with midkine (MK), a growth/differentiation factor involved in embryogenesis.
- Syndecan 2: Highly expressed in regions of morphogenetic activity such as epithelial-mesenchymal interfaces and prechondrogenic/osteogenic condensations.
- Syndecan 4: Functions cooperatively with integrins in cell spreading and focal adhesion assembly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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