Thermo Fisher Scientific IKAP Polyclonal Antibody
IKAP 단백질을 인식하는 Rabbit 폴리클로날 항체로, WB, IHC, ELISA에 사용 가능. Human, Mouse, Rat 반응성. 친화 크로마토그래피로 정제된 액상 항체이며, PBS/glycerol 버퍼에 보관. 염증 신호 관련 단백질 연구용으로 적합.
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Thermo Fisher Scientific IKAP Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:4,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1093–1332 of human IKBKAP (NP_003631.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.94 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804323 |
Product Specific Information
Immunogen sequence:
LRLVYKYNRL DIIETNVKPS ILEAQKNYMA FLDSQTATFS RHKKRLLVVR ELKEQAQQAG LDDEVPHGQE SDLFSETSSV VSGSEMSGKY SHSNSRISAR SSKNRRKAER KKHSLKEGSP LEDLALLEAL SEVVQNTENL KDEVYHILKV LFLFEFDEQG RELQKAFEDT LQLMERSLPE IWTLTYQQNS ATPVLGPNST ANSIMASYQQ QKTSVPVLDA ELFIPPKINR RTQWKLSLLD
Positive Samples: HeLa, HepG2, U-251MG, HL-60, Mouse liver, Rat liver
Cellular Location: Cytoplasm, Nucleus
Target Information
The protein encoded by this gene acts as a scaffold and regulator for three kinases involved in proinflammatory signaling. It binds NF-kappa-B-inducing kinase (NIK) and IKKs through distinct domains to form an active kinase complex. Mutations in this gene are associated with familial dysautonomia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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