
Thermo Fisher Scientific Kininogen-1 light chain Polyclonal Antibody
인간, 마우스, 랫트 반응성의 Kininogen-1 light chain 폴리클로날 항체. Western blot 및 IHC(P) 검증 완료. KLH 결합 합성 펩타이드 면역원 사용. 단백질 A 정제, 1 mg/mL 농도, -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:400 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human HMW Kininogen-1 light chain |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene uses alternative splicing to generate two different proteins: high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK).
HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Bradykinin, a peptide causing numerous physiological effects, is released from HMWK.
In contrast, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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