Thermo Fisher Scientific CSK Monoclonal Antibody (C.678.4)
CSK 단백질을 인식하는 Rabbit 모노클로널 항체로 Western blot에 최적화됨. Human, Mouse 등 다양한 종에 반응하며, Affinity chromatography로 정제된 액상 형태. CSK의 Src 억제 기능 연구에 적합한 연구용 시약.
- 판매단위
- pk
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Applications
- Western Blot (WB): 1:1,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Pig, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C.678.4 |
| Immunogen | Synthetic peptide corresponding to residues surrounding amino acid residue Val399 of human CSK |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage buffer | 0.01M HEPES (pH 7.5), 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_10982950 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with other proteins.
Target Information
CSK is a tyrosine kinase that downregulates the activity of SRC oncoprotein through phosphorylation of its carboxy terminus. The CSK gene may function as an antioncogene, playing an important role in regulating cell growth, differentiation, migration, and immune responses.
CSK phosphorylates tyrosine residues in the C-terminal tails of Src-family kinases including LCK, SRC, HCK, FYN, LYN, CSK, and YES1. It is expressed ubiquitously as a ~50 kDa cytosolic protein, with a fraction localized to lipid rafts via interaction with PAG (Csk-binding protein).
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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