Thermo Fisher Scientific MTOR Monoclonal Antibody (OTI1G4), TrueMAB
mTOR 단백질을 표적하는 Mouse monoclonal 항체로 Western blot에 최적화됨. Human 시료에 반응하며, 정제된 Lyophilized 형태로 제공. PBS buffer에 trehalose 포함, 보존제 없음. 세포 성장 및 암 연구용으로 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1766–2144 of human MTOR produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
FRAP1 (mTOR) is a serine/threonine kinase involved in cellular growth and proliferation.
Disruptions in the mTOR/PI3K/AKT pathway are linked to various cancers.
FRAP1 is the target of rapamycin and its analogs, used as immunosuppressants and cancer therapeutics.
Mutations in this gene are associated with Smith-Kingsmore syndrome.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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