Thermo Fisher Scientific OMA1 Polyclonal Antibody
Thermo Fisher Scientific의 OMA1 Polyclonal Antibody는 인간, 마우스, 랫트 시료에서 OMA1 단백질을 검출하는 토끼 유래 IgG 항체입니다. Western blot, IHC, ICC/IF에 적합하며, 액상 형태로 제공됩니다. 고순도 친화 크로마토그래피 정제 및 안정적인 PBS/glycerol 버퍼 구성으로 연구용에 최적화되어 있습니다.
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- PA5106421
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human OMA1 (Accession Q96E52), corresponding to amino acid residues K405–Q455 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2854093 |
Product Specific Information
Antibody detects endogenous levels of total OMA1.
Target Information
OMA1 (Overlapping with the m-AAA protease 1 homolog), also known as MPRP1 (Metalloprotease-related protein 1), belongs to the peptidase M48 family.
It is a zinc metalloprotease that spans the inner mitochondrial membrane with several predicted membrane-spanning domains.
The 60 kDa form of OMA1 rapidly accumulates along with cleavage of all OPA1 variants, while the 40 kDa form may represent the inactive enzyme and the 60 kDa form the active enzyme.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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