Thermo Fisher Scientific OMA1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

1:100-1:500

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human OMA1(Accession Q96E52), corresponding to amino acid residues K405-Q455. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:OMA1,uniProtId:Q96E52-1,ncbiNodeId:9606,antigenRange:405-455,antigenLength:524,antigenImageFileName:PA5-106421_OMA1_Q96E52-1_Rabbit.svg,antigenImageFileNamePDP:PA5-106421_OMA1_Q96E52-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2854093

Product Specific Information

Antibody detects endogenous levels of total OMA1.

Target Information

OMA1 (Overlapping with the m-AAA protease 1 homolog) is also named as MPRP1(Metalloprotease-related protein 1) and belongs to the peptidase M48 family. It is a zinc metalloprotease that spans the inner mitochondrial membrane with a number of predicted membrane spanning domains and the 60 kDa form of OMA1 rapidly accumulated concomitantly with the cleavage of all OPA1 variants, and the 40 kDa form of OMA1 may be the inactive form, with the 60 kDa form being the active enzyme.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.