Thermo Fisher Scientific Angiotensinogen Polyclonal Antibody
Angiotensinogen 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF 등 다양한 응용 가능. Human, Mouse, Rat 반응성. 고순도(>95%) 항체로 혈압 조절 관련 연구에 적합. 장기 보관 시 -20°C에서 안정적 유지.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human AGT |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803957 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
The protein encoded by AGT (angiotensinogen precursor) is expressed in the liver and is cleaved by renin in response to lowered blood pressure. The resulting product, angiotensin I, is further processed by angiotensin converting enzyme (ACE) to form angiotensin II, a physiologically active peptide involved in blood pressure regulation.
Mutations in this gene are associated with essential hypertension, renal tubular dysgenesis, atrial fibrillation, and inflammatory bowel disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: PA5-87208_Angiotensinogen_P01019-1_Rabbit.svg, PA5-87208_Angiotensinogen_P01019-1_Rabbit_PDP.jpeg)
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