Thermo Fisher Scientific NAV1 Polyclonal Antibody
Rabbit polyclonal antibody against human NAV1 protein. Validated for IHC (paraffin) with 1:20–1:50 dilution. Antigen affinity purified, supplied as liquid in PBS with 40% glycerol. Suitable for neuronal development and regeneration studies.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NAV1. Recombinant protein control fragment (Product #RP-90900) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2644486 |
Product Specific Information
Immunogen sequence:
AKSFVKPPSL ANLDKVNSNS LDLPSSSDTT HASKVPDLHA TSSASGGPLP SCFTPSPAPI LNINSASFSQ GLELMSGFSV PKETRMYPKL SGLHRSMESL QMPMSLPSAF PSSTPVPTPP APPAAPTEEE TEELTWSGSP
Highest antigen sequence identity to the following orthologs:
- Mouse: 91%
- Rat: 90%
Target Information
NAV1 belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. The exact function of this gene is not known, but it is thought to play a role in neuronal development and regeneration. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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